Oxytocin 10mg 15mL Nasal Spray
Oxytocin Nasal Spray is being studied for its potential to support emotional balance, stress regulation, and overall well-being. Oxytocin, often referred to as the “connection hormone,” plays a role in social bonding, mood, and relaxation pathways.
MOA
Oxytocin:
- Receptor Binding and Signal Transduction:
- Oxytocin exerts its physiological effects by binding to the oxytocin receptor (OXTR), a G-protein–coupled receptor (GPCR) expressed on target cells in the brain, uterus, mammary glands, and cardiovascular system. Receptor activation stimulates phospholipase C (PLC), leading to the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP₂) into inositol triphosphate (IP₃) and diacylglycerol (DAG). This cascade elevates intracellular calcium (Ca²⁺) levels, initiating downstream contractile and signaling responses.
- Cellular Activation and Physiologic Response:
- Increased intracellular calcium activates calmodulin-dependent kinases and the cell’s contractile machinery, producing smooth muscle contractions, most notably in uterine and mammary tissues. This mechanism underlies oxytocin’s role in labor induction, postpartum uterine tone, and milk ejection during lactation.
- Neuroendocrine and Behavioral Regulation:
- Beyond its peripheral actions, oxytocin functions as a neuropeptide in the central nervous system, influencing social bonding, trust, emotional regulation, and sexual behavior. It modulates activity in limbic and hypothalamic brain regions associated with emotional processing and stress adaptation.
- Stress Reduction and Parasympathetic Activation:
- Oxytocin dampens hypothalamic-pituitary-adrenal (HPA) axis activity, lowering cortisol levels and promoting a parasympathetic, restorative state. These effects contribute to reduced anxiety, enhanced mood, and improved stress resilience.
- Systemic and Therapeutic Effects:
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- Through its dual roles as a hormone and neuromodulator, oxytocin supports reproductive physiology, emotional connection, and autonomic balance. Its actions on smooth muscle tone, cardiovascular regulation, and social cognition make it a unique peptide bridging endocrine and behavioral health.
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This product requires a good faith medical-screening. After purchasing, you will receive instructions to schedule and complete your intake screening before your order can be fulfilled. Each intake is valid for one calendar year.
