Selank is a nootropic and anxiolytic peptide studied for its potential to support stress resilience, cognitive function, and emotional balance. It may offer neuroprotective benefits while helping to improve focus, memory, and mood.
Benefits
May help reduce anxiety and improve stress response
May enhance cognitive performance and memory
May support mood regulation and emotional well-being
May promote long-term brain health and neuroprotection
Dosing
2 sprays each nostril
Mild Anxiety/Mood or Performance Boost:
5 days on, 2 days off
Extended Use for Cognitive Enhancement or Chronic Use:
4 weeks on, cycle 1 week off
How to Use
Duration: 3 months
MOA
Anxiolytic and Stress-Reducing Effects:
Selank is a synthetic heptapeptide derived from tuftsin, an endogenous immunomodulatory peptide. It exerts potent anxiolytic effects primarily through modulation of the GABAergic system, enhancing GABA-A receptor activity to promote relaxation and reduce anxiety without sedative side effects. Selank also increases serotonin and dopamine levels in key brain regions, contributing to mood stabilization, improved emotional balance, and overall sense of well-being.
Cortisol and Stress Hormone Regulation:
By downregulating corticotropin-releasing hormone (CRH) and reducing cortisol secretion, Selank attenuates the physiological stress response mediated by the hypothalamic-pituitary-adrenal (HPA) axis. This effect helps counteract chronic stress, anxiety, and stress-induced fatigue.
Cognitive Enhancement and Neuroplasticity:
Selank enhances cognitive performance by increasing the expression of brain-derived neurotrophic factor (BDNF), a critical protein involved in neurogenesis, synaptic plasticity, and memory formation. It also optimizes dopaminergic and noradrenergic signaling, supporting improved focus, learning, and mental clarity.
Neuroprotection and Antioxidant Effects:
Through its influence on neurotrophic and neurotransmitter pathways, Selank enhances neuronal resilience to oxidative stress and inflammatory injury. These neuroprotective actions may help preserve brain function and delay cognitive decline under conditions of stress or aging.
Immune and Anti-Inflammatory Modulation:
Selank exhibits mild immunoregulatory effects, modulating cytokine production and reducing neuroinflammation that contributes to stress-related or inflammatory cognitive dysfunction. By restoring immune balance and reducing systemic inflammation, it supports both neurological and overall physiologic homeostasis.
Systemic Impact:
Through the integration of GABAergic modulation, neurotransmitter balance, and anti-inflammatory effects, Selank provides a multifaceted approach to improving mood, cognition, and stress resilience, supporting emotional stability and brain health.
More Information
Disclaimer: For Research Purposes Only – All products on this site are for Research and Development use only. The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease. Celia Health is a supplier of research-use chemicals manufactured in a CGMP facility in the US. Celia Health is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic act.
This product requires a prescription. After purchasing, you will receive instructions to schedule and complete your intake exam before your order can be fulfilled. Prescriptions are valid for one calendar year.