SS-31 25mg 15mL Nasal Spray
$395.00
|$356.00 with Automatic Refills
SS-31 (Elamipretide) is a mitochondria-targeting peptide being studied for its antioxidant and protective effects. It may help reduce cellular damage from mitochondrial dysfunction, supporting brain, heart, muscle, and metabolic health—particularly in the context of aging and chronic disease.
MOA
- Mitochondrial Targeting and Accumulation:
- SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide designed to selectively accumulate within the inner mitochondrial membrane (IMM), the site of oxidative phosphorylation and ATP synthesis. Its unique aromatic–cationic structure allows it to penetrate cellular and mitochondrial membranes efficiently, concentrating at the heart of cellular energy production.
- Inner Mitochondrial Membrane Stabilization:
- By binding to cardiolipin, a phospholipid critical for maintaining mitochondrial membrane integrity, SS-31 stabilizes the structure and function of the IMM. This interaction optimizes electron transport chain (ETC) efficiency, reduces electron leak, and minimizes the generation of reactive oxygen species (ROS), thereby preserving mitochondrial potential and bioenergetic capacity.
- Enhanced ATP Production and Cellular Energy:
- Through improved ETC coupling and membrane stabilization, SS-31 enhances ATP synthesis and overall mitochondrial efficiency. These effects restore energy balance in high-demand tissues such as cardiac, skeletal muscle, and neural cells, improving cellular performance under metabolic stress.
- Cytoprotective and Anti-Apoptotic Effects:
- SS-31 protects cells from apoptosis by reducing mitochondrial stress, preventing cytochrome c release, and inhibiting downstream caspase activation. This protection maintains cellular viability during oxidative, ischemic, or inflammatory injury.
- Reduction of Oxidative and Inflammatory Stress:
- By decreasing ROS production and improving mitochondrial redox balance, SS-31 mitigates oxidative damage and downstream inflammatory signaling. This contributes to improved tissue recovery and resilience in conditions of mitochondrial dysfunction.
- Systemic Benefits and Longevity Support:
- Through restoration of mitochondrial function, SS-31 supports cellular longevity, metabolic stability, and improved organ function across systems affected by mitochondrial decline, particularly the heart, brain, and skeletal muscle.
More Information
- Disclaimer: For Research Purposes Only – All products on this site are for Research and Development use only. The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease. Celia Health is a supplier of research-use chemicals manufactured in a CGMP facility in the US. Celia Health is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic act.
This product requires a prescription. After purchasing, you will receive instructions to schedule and complete your intake exam before your order can be fulfilled. Prescriptions are valid for one calendar year.
