Sermorelin 15mg 15mL Nasal Spray: Automatic Refills
$346.50
1 month supply
Rx
Sermorelin is a growth hormone-releasing peptide that stimulates the body’s natural production of growth hormone, promoting improved sleep, enhanced muscle growth, fat loss, and overall vitality.
MOA
- Growth Hormone–Releasing Hormone (GHRH) Analog:
- Sermorelin is a synthetic analog of endogenous growth hormone–releasing hormone (GHRH) that stimulates the anterior pituitary to produce and secrete human growth hormone (HGH) naturally. By binding to GHRH receptors on pituitary somatotrophs, it initiates the physiologic release of GH in a pulsatile manner, preserving the body’s natural secretion rhythm.
- Pituitary Activation and GH Pulsatility:
- Through direct activation of pituitary GHRH receptors, Sermorelin enhances pulsatile GH secretion while maintaining hypothalamic-pituitary feedback regulation. This physiologic stimulation avoids pituitary overstimulation and supports long-term endocrine balance, distinguishing it from exogenous GH therapy.
- IGF-1 Stimulation and Anabolic Effects:
- Increased GH output triggers hepatic production of insulin-like growth factor-1 (IGF-1), a key mediator of tissue repair, protein synthesis, and cellular regeneration. Elevated IGF-1 promotes improved body composition, muscle recovery, and metabolic vitality.
- Hypothalamic–Pituitary Axis Preservation:
- Unlike direct GH administration, Sermorelin maintains the integrity of the hypothalamic-pituitary axis (HPA) by allowing normal feedback inhibition via somatostatin and IGF-1 signaling. This regulation minimizes the risk of receptor downregulation, GH overproduction, or shutdown of endogenous hormone synthesis.
- Metabolic and Recovery Support:
- By enhancing natural GH pulsatility and IGF-1 levels, Sermorelin supports lipolysis, cellular repair, and tissue regeneration. These effects contribute to improved sleep quality,
More Information
- Disclaimer: For Research Purposes Only – All products on this site are for Research and Development use only. The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease. Celia Health is a supplier of research-use chemicals manufactured in a CGMP facility in the US. Celia Health is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic act.
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