Tesamorelin is a GHRH (Growth Hormone-Releasing Hormone) analog that stimulates the body’s natural production of growth hormone. It’s being studied for its potential to reduce visceral fat, support lean muscle, enhance metabolism, and promote healthy aging through more natural, rhythmic hormone release.
Benefits
May help reduce visceral fat
May stimulate natural HGH production
May support lean muscle maintenance
May improve cognitive function
May enhance sleep quality and recovery
Dosing
Dose: 1mg
Draw 80 units (0.8mL) per dose for 1mg
5 days per week (M-F), 2 consecutive days off
Administer at night 1-hour before bed, on an empty stomach
How to Use
Duration: 3 months
Reconstitute: add 8mL bacteriostatic water to the 10mg vial of Tesamorelin
Subcutaneous injection
MOA
Growth Hormone–Releasing Hormone (GHRH) Analog:
Tesamorelin is a synthetic analog of endogenous GHRH that binds to pituitary GHRH receptors, stimulating the pulsatile release of growth hormone (GH). This activation leads to increased circulating insulin-like growth factor-1 (IGF-1) levels, driving multiple anabolic and metabolic effects.
Visceral Fat Reduction and Lipolysis:
Through activation of the GH/IGF-1 axis, Tesamorelin promotes lipolysis with preferential reduction of visceral adipose tissue. This targeted fat loss contributes to improved body composition and metabolic efficiency.
Muscle Protein Synthesis and Body Composition:
Enhanced GH signaling supports muscle anabolism by stimulating amino acid uptake and protein synthesis within skeletal muscle. This promotes lean mass development and overall improvement in muscle-to-fat ratio.
Hepatic and Metabolic Regulation:
Tesamorelin indirectly improves hepatic lipid metabolism by decreasing intrahepatic fat content and enhancing insulin sensitivity. The reduction in triglycerides and elevation in adiponectin levels further contribute to improved metabolic balance.
Mitochondrial Biogenesis and Cellular Energy:
Upregulation of IGF-1 signaling enhances mitochondrial biogenesis, optimizing cellular energy production and metabolic resilience during periods of caloric restriction or metabolic stress.
Cognitive and Neurogenic Support:
GH and IGF-1 activity influence hippocampal neurogenesis, supporting cognitive health and memory function. This neurotrophic effect may be mediated by increased brain-derived neurotrophic factor (BDNF) expression.
Sleep and Recovery:
Tesamorelin promotes natural GH pulsatility, which is closely tied to deep (slow-wave) sleep cycles. Improved GH rhythms enhance recovery, tissue repair, and hormonal balance.
Cardiovascular and Metabolic Homeostasis:
By improving lipid metabolism, reducing visceral fat, and supporting endothelial function, Tesamorelin contributes to overall cardiovascular health and systemic metabolic homeostasis.
More Information
Disclaimer: For Research Purposes Only – All products on this site are for Research and Development use only. The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease. Celia Health is a supplier of research-use chemicals manufactured in a CGMP facility in the US. Celia Health is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic act.
This product requires a good faith medical-screening. After purchasing, you will receive instructions to schedule and complete your intake screening before your order can be fulfilled. Each intake is valid for one calendar year.
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